hrp0084p3-855 | Fat | ESPE2015

Plasminogen Activator Inhibitor-1 as a Marker of Insulin Resistance in Obese Adolescents

Engiz Ozlem , Alioglu Bulent , Bagrul Denizhan , Karakaya Jale , Dallar Yildiz Bilge

Background: Obesity is considered to be a chronic inflammatory state in which the dysfunction of adipose tissue plays a central role. Adipose tissue is known to express and secrete a variety of products known as ‘adipokines’ including leptin, adiponectin, resistin, and visfatin, as well as cytokines and chemokines such as tumor necrosis factor-α (TNF-α), interleukin-6, and monocyte chemoattractant protein-1.Objective and hypotheses: T...